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To acquire analogs of compound X, the commencing acid two was reacted having an surplus of dimethyl sulphate as well as the received spinoff 3 was subjected to some multidirectional synthesis (Plan three). In the 1st circumstance, bromine was introduced to the methyl group to offer a compound 3d, by response with NBS in CCl4. Within the reaction wi

This complete method of lawful higher dependancy cure provides you with the chance to rebuild by yourself from the bottom up.From the 3rd route, ester 3 was hydrolyzed in alkaline situations to acid 3b, and finally this derivative was transformed to an amide 3c by reaction with oxalyl chloride and ammonium hydroxide. Importantly, every one of the n